869845-40-9Relevant articles and documents
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 (N-fluoroalkyl) labeled 2β-carbomethoxy-3β-(4′-(3- furyl)phenyl)-tropanes and -nortropanes: Candidate radioligands for in vivo imaging of the serotonin transporter with posi
Stehouwer, Jeffrey S.,Plisson, Christophe,Jarkas, Nachwa,Zeng, Fanxing,Voll, Ronald J.,Williams, Larry,Martarello, Laurent,Votaw, John R.,Tamagnan, Gilles,Goodman, Mark M.
, p. 7080 - 7083 (2005)
2β-Carbomethoxy-3β-(4′-(3-furyl)phenyl)nortropane (1) was synthesized along with the N-methyl (2), N-fluoroethyl (3), N-fluoropropyl (4), and N-fluorobutyl (5) derivatives. The binding affinity for each compound to the human serotonin, dopamine, and norep