869857-98-7

Upstream product

• 869857-96-5 (2S,3S,4R,5S)-1-benzyloxycarbonyl-2-carboxy-5-methylpyrrolidine-3,4-diol 
• 95-54-5 1,2-diamino-benzene 
• 869857-92-1 (2S,3S,4R,5S)-1-benzyloxycarbonyl-2-formyl-5-methylpyrrolidine-3,4-diol 

Downstream Products

• 869857-99-8 (2S,3S,4R,5S)-2-(1H-benzoimidazol-2-yl)-1-benzyloxycarbonyl-3,4-isopropylidenedioxy-5-methylpyrrolidine 

Relevant academic research and scientific papers

Synthesis of novel pyrrolidine 3,4-diol derivatives as inhibitors of α-L-fucosidases

The stereoselective synthesis of new 3,4-dihydroxypyrrolidine derivatives starting from D-mannose, D-ribose and L-fucose is presented. Two synthetic strategies employing organometallic addition to hemiacetalic sugars followed by selective nucleophilic dis

Stereoselective synthesis of (2S,3S,4R,5S)-5-methylpyrrolidine-3,4-diol derivatives that are highly selective α-L-fucosidase inhibitors

N-Phenylaminomethyl benzimidazolyl moieties attached at C-2 of (2S,3S,4R,5S)-5-methylpyrrolidine-3,4-diol increase the potency and selectivity of the inhibitory activity of these systems towards α-L-fucosidases. The Royal Society of Chemistry 2005.