869882-08-6

Usage

Physical form

White crystalline solid

Solubility

Insoluble in water

Uses

+ Intermediate in the synthesis of pharmaceuticals and agrochemicals
+ Building block in organic synthesis
+ Reagent in chemical reactions
+ Potential ligand in coordination chemistry
+ Precursor for the preparation of various functional materials

Industrial and research significance

Unique chemical properties and reactivity.

Upstream product

• 862374-11-6 2,6-bis(trifluoromethyl)benzyl bromide 
• 143-33-9 sodium cyanide 

Relevant academic research and scientific papers

Method for the treatment of CNS disorders with substituted 2-imidazoles or imidazole derivatives

The present invention relates a method for treating depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders such as schizophrenia, neurological diseases such as Parkinson's disease, neurodegenerative disorders such as Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse and metabolic disorders such as eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders which comprises administering to an individual a therapeutically effective amount of a compound of formula I wherein R, R1, R2, A and n are as defined in the specification and to their pharmaceutically active salts. The invention also relates to novel compounds of formula I, pharmaceutical compositions containing them, and methods for their preparation.