869892-31-9Relevant academic research and scientific papers
Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a cb1 receptor antagonist with in vivo antiobesity effect
Srivastava, Brijesh Kumar,Soni, Rina,Patel, Jayendra Z.,Joharapurkar, Amit,Sadhwani, Nisha,Kshirsagar, Samadhan,Mishra, Bhupendra,Takale, Vijay,Gupta, Sunil,Pandya, Purvi,Kapadnis, Prashant,Solanki, Manish,Patel, Harilal,Mitra, Prasenjit,Jain, Mukul R.,Patel, Pankaj R.
, p. 2546 - 2550 (2009)
A few thienyl substituted pyrazole derivatives were synthesized to aid in the characterization of the cannabinoid receptor antagonist and also to serve as potentially useful antiobesity agent. Structural requirements for selective CB1 receptor antagonistic activity of 5-thienyl pyrazole derivatives included the structural similarity with potent, specific antagonist rimonabant 1. Compound 3 has been identified as a hair growth stimulator and an antiobesity agent in animal models.
SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS
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Page/Page column 28, (2010/11/27)
This invention is directed to a substituted 5-heteroaryl-1-phenyl-pyrazole cannabinoid modulator compound of formula (I): or a form thereof, and methods for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or
