86998-56-3Relevant academic research and scientific papers
DESULPHURATIVE APPROACHES TO PENEM ANTIBIOTICS. II. 4-ACYLDITHIOAZETIDIN-2-ONES FROM PENICILLIN DERIVED SULPHENIMIDES, THIOLSULPHONATES AND DISULPHIDES.
Alpegiani, Marco,Badeschi, Angelo,Foglio, Maurizio,Giudici, Franco,Perrone, Ettore
, p. 1627 - 1630 (2007/10/02)
Displacement of different leaving groups from a number of 2-oxo-azetidin-4-ylthio derivatives with thioacids, followed by sulphur extrusion, provides a facile access to β-lactam thioesters and hence to penems.
