87001-69-2

Upstream product

• 87001-64-7 (-)neocarvomenthyl carbonitrile 

Downstream Products

• 87001-67-0 (+)carvomenthyl formic acid 
• 87001-71-6 (1R,2S,5S)-5-Isopropyl-2-methyl-cyclohexanecarbonyl chloride 
• 87001-66-9 (+)(1S,2S,4S) 1-methyl-4-isopropyl-cyclohexyl-2-carboamide 
• 87001-68-1 (-)(1S,2R,4S) 1-methyl-4-isopropyl-cyclohexyl-2-carboamide 
• 87001-70-5 (1S,2S,5S)-5-Isopropyl-2-methyl-cyclohexanecarbonyl chloride 

Relevant academic research and scientific papers

Reaction of (+)carvomenthol tosylate with KCN in aprotic solvents; (1S,2R,4S) 1-methyl-4-isopropylcyclohexane-2-carbonitrile

Reaction of (+)carvomenthol tosylate with KCN in pyridine solution was proved to produce a mixture of hydrocarbons; in DMF additionally a small quantity of alcohols was obtained.However, in DMSO sterically homogeneous (-)(1S,2R,4S) 1-methyl-4-isopropylcyclohexane-2-carbonitrile ((-)neocarvomenthyl carbonitrile) was the main product.The structure of the compound obtained was determined on the basis of spectral data, elemental analysis, and chemical transformations which indicated configurational relation of the title compound to the known (-)(1S,2R,4S) neocarvomenthyl amine.