870093-45-1

Basic information

• Product Name: (2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-3-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-2-methoxy-N-((S)-2-oxo-azepan-3-yl)-propionamide
• Synonyms: (2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-3-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-2-methoxy-N-((S)-2-oxo-azepan-3-yl)-propionamide
• CAS NO: 870093-45-1
• Molecular Weight: 470.682
• Mol File: 870093-45-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-3-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-2-methoxy-N-((S)-2-oxo-azepan-3-yl)-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-3-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-2-methoxy-N-((S)-2-oxo-azepan-3-yl)-propionamide(870093-45-1)
• EPA Substance Registry System: (2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-3-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-2-methoxy-N-((S)-2-oxo-azepan-3-yl)-propionamide(870093-45-1)

Safety Data

• Hazardous Substances Data: 870093-45-1(Hazardous Substances Data)

Upstream product

• 870093-43-9 (2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-3-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-2-methoxy-propionic acid 
• 21568-87-6 2-aminocaprolactam 

Downstream Products

• 1239970-79-6 C₂₉H₅₂N₂O₆Si 
• 870093-68-8 (2R,3R)-3-[(4R,5R)-2,2-Dimethyl-5-((E)-styryl)-[1,3]dioxolan-4-yl]-3-hydroxy-2-methoxy-N-((S)-2-oxo-azepan-3-yl)-propionamide 

Relevant articles and documents

Total synthesis of bengamide E and analogues by modification at C-2 and at terminal olefinic positions

The total synthesis of the natural product Bengamide E, one of the members of a new class of antitumor natural products of marine origin, is reported based on a convergent and flexible synthetic route featuring an oxirane ring-opening reaction and an olefin cross metathesis. In a similar way, analogues structurally modified at C-2 and at the terminal vinyl positions were prepared by introduction of various nucleophiles and alkyl substituents during the epoxide opening and the olefin cross metathesis steps, respectively. These studies demonstrate the validity of our synthetic strategy, although they reveal some problems associated with the olefin cross metathesis, whose efficiency depends on the substituent at the C-2 position as well as the steric environment of the alkene.