870095-92-4Relevant academic research and scientific papers
Total synthesis of the marine natural product (-)-clavosolide A
Barry, Conor S.,Elsworth, Jon D.,Seden, Peter T.,Bushby, Nick,Harding, John R.,Alder, Roger W.,Willis, Christine L.
, p. 3319 - 3322 (2006)
The total synthesis of the marine metabolite clavosolide A is reported which confirms the structure and absolute configuration of the natural product as the symmetrical diolide glycosylated by permethylated D-xylose moieties, 2.
Total synthesis of a diastereomer of the marine natural product clavosolide A
Barry, Conor S.,Bushby, Nick,Charmant, Jonathan P. H.,Elsworth, Jon D.,Harding, John R.,Willis, Christine L.
, p. 5097 - 5099 (2007/10/03)
The first total synthesis of the reported structure of the sponge metabolite clavosolide A is described using a Prins cyclisation to assemble the tetrahydropyran core followed by manipulation of the side-chain, dimerisation and finally glycosidation. The Royal Society of Chemistry 2005.
