87010-29-5 Usage
Uses
Used in Pharmaceutical Industry:
3-(3-Hydroxypropyl)-2-oxazolidinone is used as a key intermediate in the preparation of Ifosfamide and its analogs, which are chemotherapeutic agents used in the treatment of various types of cancer. Its unique chemical structure allows for the development of novel therapeutic agents with improved efficacy and reduced side effects.
Flammability and Explosibility
Nonflammable
Check Digit Verification of cas no
The CAS Registry Mumber 87010-29-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,0,1 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87010-29:
(7*8)+(6*7)+(5*0)+(4*1)+(3*0)+(2*2)+(1*9)=115
115 % 10 = 5
So 87010-29-5 is a valid CAS Registry Number.
87010-29-5Relevant academic research and scientific papers
Synthesis of side-chain-substituted ifosfamide analogs
Paci,Guillaume,Husson
, p. 1131 - 1134 (2007/10/03)
Three analogs of the cytostatic drug ifosfamide incorporating 1-methyl-2-chloroethyl side chains were designed and prepared as an attempt to obtain drugs of lower toxicity.
Synthesis and antitumor activity of two ifosfamide analogs with a five-membered ring
Kutscher,Niemeyer,Engel,Kleemann,Hilgard,Pohl,Scheffler
, p. 323 - 326 (2007/10/02)
Two ifosfamide (CAS 3778-73-2) analogs with a five-membered ring, i.e. the oxazaphospholidine derivatives 6 and 7, were synthesized and their cytotoxic activity in vitro, acute toxicity and antitumor activity in vivo determined in comparison with the oxaz