87014-67-3Relevant academic research and scientific papers
Controlling stereoselection in aza-Cope-Mannich reactions
Overman, Larry E.,Trenkle, William C.
, p. 23 - 30 (2007/10/03)
The synthesis of 2-substituted cis-octahydroindolones from the reaction of cis-2-amino-1-alkenylcyclopentanols with aldehydes was studied to examine whether stereoselection in the aza-Cope-Mannich reaction could be controlled by the nature of the nitrogen
SYNTHESIS APPLICATIONS OF AZA-COPE REARRANGEMENTS. STEREOSELECTIVE SYNTHESIS OF TRANS-2-ALKYL-CIS-3a-ARYLOCTAHYDROINDOLONES.
Overman, Larry E.,Mendelson, Leah T.,Flippin, Lee A.
, p. 2733 - 2736 (2007/10/02)
The reaction of both cis- and trans-2-amino-1-(1-phenylvinyl)-cyclopentanols with aldehydes affords trans-2-alkyl-cis-3a-aryl-4-oxo-octahydroindoles stereoselectively.
