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CAS

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87018-59-5

(+/-)11-HDOHE, also known as 11-hydroxy-5,8,12,14-(Z,Z,E,Z)-eicosatetraenoic acid, is a bioactive lipid mediator derived from omega-3 fatty acids. It is formed through the metabolism of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) by the action of lipoxygenase enzymes. (+/-)11-HDOHE exhibits potent anti-inflammatory and anti-oxidative properties and plays a role in the regulation of blood pressure, immune function, and lipid metabolism. Its potential therapeutic applications include the treatment of cardiovascular disease, cancer, and other inflammatory disorders. The diverse biological activities of (+/-)11-HDOHE make it a promising target for further research and development of new therapeutic strategies.

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  • 4,7,9,13,16,19-Docosahexaenoicacid, 11-hydroxy-, (4Z,7Z,9E,13Z,16Z,19Z)-

    Cas No: 87018-59-5

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  • 87018-59-5 Structure

  • Basic information

    1. Product Name: (+/-)11-HDOHE
    2. Synonyms: 11-HYDROXY DOCOSAHEXAENOIC ACID;(+/-)11-HDOHE;(±)11-HDHA;(+/-)11-HYDROXY-4Z,7Z,9E,13Z,16Z,19Z-DOCOSAHEXAENOIC ACID;LTERDCBCHFKFRI-BGKMTWLOSA-N
    3. CAS NO:87018-59-5
    4. Molecular Formula: C22H32O3
    5. Molecular Weight: 344.48768
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 87018-59-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (+/-)11-HDOHE(CAS DataBase Reference)
    10. NIST Chemistry Reference: (+/-)11-HDOHE(87018-59-5)
    11. EPA Substance Registry System: (+/-)11-HDOHE(87018-59-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 87018-59-5(Hazardous Substances Data)

87018-59-5 Usage

Uses

Used in Pharmaceutical Industry:
(+/-)11-HDOHE is used as a therapeutic agent for its anti-inflammatory and anti-oxidative properties, which can help in the treatment of cardiovascular disease, cancer, and other inflammatory disorders.
Used in Nutraceutical Industry:
(+/-)11-HDOHE is used as a dietary supplement to support overall health and well-being by promoting the regulation of blood pressure, immune function, and lipid metabolism.
Used in Research and Development:
(+/-)11-HDOHE is used as a target for further research to better understand its precise mechanisms of action and physiological effects, which can lead to the development of new therapeutic strategies and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 87018-59-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,0,1 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87018-59:
(7*8)+(6*7)+(5*0)+(4*1)+(3*8)+(2*5)+(1*9)=145
145 % 10 = 5
So 87018-59-5 is a valid CAS Registry Number.

87018-59-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 11-hydroxydocosa-4,7,9,13,16,19-hexaenoic acid

1.2 Other means of identification

Product number -
Other names 11-hydroxy DHA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:87018-59-5 SDS

87018-59-5Upstream product

87018-59-5Downstream Products

87018-59-5Relevant articles and documents

OXYLIPINS FROM LONG CHAIN POLYUNSATURATED FATTY ACIDS AND METHODS OF MAKING AND USING THE SAME

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Page/Page column 59, (2008/06/13)

Disclosed are novel oxylipins, referred to herein as docosanoids, that are derived from C22 polyunsaturated fatty acids, and method of making and using such oxylipins. Also disclosed is the use of docosapentaenoic acid (C22:5n-6) (DPAn-6), docosapentaenoic acid (C22:5n-3) (DPAn-3), and docosatetraenoic acid (DTAn-6: C22:4n-6) as substrates for the production of novel oxylipins, and to the oxylipins produced thereby. Also disclosed is the use of DPAn-6, DPAn-3, DTAn-6, and/or the oxylipins derived therefrom, and/or novel docosanoids derived from the structures of C22 fatty acids, in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. The invention also relates to novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of LCPUFA-derived oxylipins, and particularly, docosanoids.

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