870190-27-5Relevant academic research and scientific papers
Identification of novel and improved antimitotic agents derived from noscapine
Anderson, James T.,Ting, Anthony E.,Boozer, Sherry,Brunden, Kurt R.,Crumrine, Chris,Danzig, Joel,Dent, Tom,Faga, Laurel,Harrington, John J.,Hodnick, William F.,Murphy, Steven M.,Pawlowski, Gary,Perry, Robert,Raber, Amy,Rundlett, Stephen E.,Stricker-Krongrad, Alain,Wang, Jianmin,Bennani, Youssef L.
, p. 7096 - 7098 (2005)
Analogues of the natural product noscapine were synthesized and their potential as antitumor agents evaluated. The discovery of a novel regioselective O-demethylation facilitated the synthesis of the potent aniline 6, which arrests mammalian cells in the
Benzo[1,3]dioxole compounds, pharmaceutical compositions thereof, and processes of making and using the same
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Page/Page column 25; 26, (2010/02/11)
The present invention relates to benzo[1,3]dioxole compounds and pharmaceutical compositions containing such compounds. These compounds and compositions may be made by various methods. These compounds and compositions may be used to treat disorders and diseases such as cancer.
