87022-34-2Relevant academic research and scientific papers
Synthesis of 1-Isocyanomethyl Azoles and Related Compounds
Saikachi, Haruo,Sasaki, Hideaki,Kitagawa, Tokujiro
, p. 723 - 726 (2007/10/02)
1-Isocyanomethyl azoles (11a-f) with trimethylformamidomethylammonium iodide (8), followed by dehydration of the resulting 1-formamidomethyl azoles (13a-f) using phosphorus oxychloride or triphenylphosphine/carbon tetrachloride.Furthermore, 1-substituted methyl-5-piperidinomethyltetrazoles(15a-f) were prepared by means of the four-component condensation of 14a-f with formaldehyde, sodium azide, and piperidine.Keywords - isocyanide; formamide; dehydration; azole; four-component condensation
