87022-50-2Relevant academic research and scientific papers
A FACILE SYNTHESIS OF n>CYCLOPHANES, IN WHICH AROMATIC RINGS ARE CONNECTED WITH -CH2-CO-CH2- BRIDGES
Kurosawa, Kazunori,Suenaga, Masahiko,Inazu, Takahiko,Yoshino, Tamotsu
, p. 5335 - 5338 (1982)
The title compounds, I, were synthesized by the dialkylation of TosMIC, II, with appropriate bis(halomethyl) compounds, III, under phase-transfer condition, followed by acid hydrolysis.
Synthesis of Heterophanes Containing the Pyridine, Furan, and Thiophene Rings by the TosMIC Method
Shinmyozu, Teruo,Hirai, Yoshio,Inazu, Takahiko
, p. 1551 - 1555 (2007/10/02)
(2,5)- and (2,6)pyridinophanes as well as metacyclo(2,5)furanophane (20) and metacyclo(2,5)thiophenophane (23) have been synthesized by the conventional or modified TosMIC coupling reaction, followed by acid treatment and reduction. 1H NMR data suggest that the stable conformation of the metacyclophane-2,11-dione system (3,6,19, and 22) is anti, whereas that of the metacyclophane system (4, 7, 20, and 23) is syn.In (2,5)pyridinophanes (17a-d) the average deshielding effects for protons located pseudogeminal and pseudoortho to a nitrogen atom are found to be 0.28 and 0.15 ppm, respectively, as compared to those pseudopara to the nitrogen.
Synthesis of n> Cyclophanes and Related Compounds by Alkylation of Tosylmethyl Isocyanide with Bis(bromoethyl)benzenes
Sasaki, Hideaki,Kitagawa, Tokujiro
, p. 2868 - 2878 (2007/10/02)
Bis(2-isocyano-2-tosylethyl)benzenes (12a, 12b, and 12c), synthesized by the reaction of tosylmethyl isocyanide (7) with bis(bromomethyl)benzenes (11a, 11b, and 11c) in 2:1 molar ratio, reacted again with 11a, 11b, and 11c under phase-transfer conditions
