87050-09-7

Basic information

• Product Name: (2S,3S,4S)-5-Cyano-6-methoxy-2-(4-methoxy-phenyl)-3-methyl-3,4-dihydro-2H-pyran-4-carboxylic acid methyl ester
• CAS NO: 87050-09-7
• Molecular Weight: 317.342
• Mol File: 87050-09-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,4S)-5-Cyano-6-methoxy-2-(4-methoxy-phenyl)-3-methyl-3,4-dihydro-2H-pyran-4-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4S)-5-Cyano-6-methoxy-2-(4-methoxy-phenyl)-3-methyl-3,4-dihydro-2H-pyran-4-carboxylic acid methyl ester(87050-09-7)
• EPA Substance Registry System: (2S,3S,4S)-5-Cyano-6-methoxy-2-(4-methoxy-phenyl)-3-methyl-3,4-dihydro-2H-pyran-4-carboxylic acid methyl ester(87050-09-7)

Safety Data

• Hazardous Substances Data: 87050-09-7(Hazardous Substances Data)

Upstream product

• 54797-29-4 dimethyl 2-cyanofumarate 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 

Relevant articles and documents

Transition from Concerted to Stepwise Cycloaddition Reactions of α,β-Unsaturated Carboxylic Esters

The stereospecificity of the cycloaddition reaction of electrophilic α,β-unsaturated esters with cis- and trans-propenyl ethers and with trans-anethole, leading to 3,4-dihydro-2H-pyran derivatives, is studied.Reactions with trisubstituted electrophilic olefins are stereospecific and are considered to be concerted, except with methyl 4,4,4-trichloro-2-cyanocrotonate where accompanying cyclobutane formation indicates some stepwise behavior.With tetrasubstituted electrophilic olefins, the reaction products are not stereospecific, and simultaneous cyclobutane formation also indicates stepwise behavior.The reactivity of these olefins is determined by their electronegativity, but the transition from a concerted to a stepwise mechanism appears to be governed by steric hindrance.