87052-58-2Relevant academic research and scientific papers
A SIMPLE METHOD FOR SYNTHESIS OF AMIDES AND PEPTIDES THROUGH ACYL CHLORIDES. A RAPID SYNTHESIS OF THYROTROPIN RELEASING HORMONE
Matsuda, Fuyuhiko,Itoh, Shin,Hattori, Noritaka,Yanagiya, Mitsutoshi,Matsumoto, Takeshi
, p. 3625 - 3631 (1985)
By improvement of the classical SOCl2-pyridine method for the preparation of acid chlorides, amides and optically pure peptides were synthesized rapidly in a simple manner from DCHA (dicyclohexylammonium) salts of carboxylic acids.This modified SOCl2-pyridine method was applied to a rapid synthesis of TRH.
