87066-94-2

Basic information

• Product Name: (2-PIPERIDIN-1-YL-PHENYL)METHANOL
• Synonyms: (2-PIPERIDIN-1-YL-PHENYL)METHANOL;(2-Piperidin-1-yl-phenyl)methanol95%;(2-Piperidinophenyl)methanol;Zinc02563835
• CAS NO: 87066-94-2
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.27
• Mol File: 87066-94-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 343.2°C at 760 mmHg
• Flash Point: 177.5°C
• Appearance: /
• Density: 1.089g/cm³
• Vapor Pressure: 2.74E-05mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (2-PIPERIDIN-1-YL-PHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-PIPERIDIN-1-YL-PHENYL)METHANOL(87066-94-2)
• EPA Substance Registry System: (2-PIPERIDIN-1-YL-PHENYL)METHANOL(87066-94-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 87066-94-2(Hazardous Substances Data)

Usage

General Description

(2-Piperidin-1-yl-phenyl)methanol is a chemical compound with a molecular formula C13H17NO. It is a member of the piperidine class of compounds and contains a piperidine ring along with a phenyl and a hydroxyl group. (2-PIPERIDIN-1-YL-PHENYL)METHANOL has a variety of potential applications, including as a building block in organic synthesis and as a precursor for the production of pharmaceuticals and other fine chemicals. It may also have biological activity and potential use as a drug or therapeutic agent. Additionally, this compound may be used in the development of new materials, such as polymers and resins. Overall, (2-piperidin-1-yl-phenyl)methanol has potential as a versatile and valuable chemical building block with a range of applications in various industries.

InChI:InChI=1/C12H17NO/c14-10-11-6-2-3-7-12(11)13-8-4-1-5-9-13/h2-3,6-7,14H,1,4-5,8-10H2

Upstream product

• 81215-42-1 2-(piperidin-1-yl)benzoic acid methyl ester 
• 34595-26-1 2-(piperidin-1-yl)benzaldehyde 
• 110-89-4 piperidine 
• 394-35-4 methyl 2-fluorobenzoate 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 34595-26-1 2-(piperidin-1-yl)benzaldehyde 
• 87067-07-0 2,3,4,4a-tetrahydro-1H,6H-pyrido<1,2-a><3,1>benzoxazine 
• 117323-52-1 3-Methoxy-2-[2-(2-piperidin-1-yl-benzylsulfanyl)-imidazol-1-yl]-pyridine 
• 117323-51-0 3-Methyl-2-[2-(2-piperidin-1-yl-benzylsulfanyl)-imidazol-1-yl]-pyridine 
• 117323-54-3 2-[2-(2-Piperidin-1-yl-benzylsulfanyl)-imidazol-1-yl]-pyridine 
• 173069-82-4 1-(2-Chloromethyl-phenyl)-piperidine 

Relevant articles and documents

NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST

The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R1 represents a hydrogen atom, an optionally substituted alkyl group, or the like; R2 represents a hydrogen atom, a halogen atom, or the like; and R3 represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.

RECEPTOR FUNCTION REGULATING AGENT

An agent for regulating 14273 receptor function, which is useful as a preventing or treating drug for diabetes mellitus, hyperlipidemia or the like, is provided. An agent for regulating 14273 receptor function comprising a compound containing an aromatic ring and a group capable of releasing a cation.

2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6- tetrahydrocyclopent[d]imidazoles as a novel class of gastric H+/K+-ATPase inhibitors

Substituted 2-sulfinylimidazoles were synthesized and investigated as potential inhibitors of gastric H+/K+-ATPase. The 4,5-unsubstituted imidazole series 6-11 and the 1,4,5,6-tetrahydrocyclopent[d]imidazole series 12 were found to be potent inhibitors of the acid secretory enzyme H+/K+- ATPase. Structure-activity relationships indicate that the substitution of 2- pyridyl groups at the 1-position of the imidazole moiety combined with (2- aminobenzyl)sulfinyl groups at the 2-position leads to highly active compounds with a favorable chemical stability. Other substitution patterns in the imidazole moiety result in reducing biological activities. 2-[(2- Aminobenzyl)sulfinyl]-1-[2-(3-methylpyridyl)]-1,4,5,6- tetrahydrocyclopent[d]imidazole (12h, T-776) was selected for further development as a potential clinical candidate. Extensive study on the acid degradation of 12h indicates a mechanism of action different from that of omeprazole, the first H+/K+-ATPase inhibitor introduced to the market.