870674-07-0

Basic information

• Product Name: (+)-(1R,4S)-1-(2-bromomethyl-3,6-dimethoxybenzyl)-3-ethoxy-4-methyl-1,4-dihydropyrazino[2,1-b]quinazolin-6-one
• CAS NO: 870674-07-0
• Molecular Weight: 500.392
• Mol File: 870674-07-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-(1R,4S)-1-(2-bromomethyl-3,6-dimethoxybenzyl)-3-ethoxy-4-methyl-1,4-dihydropyrazino[2,1-b]quinazolin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(1R,4S)-1-(2-bromomethyl-3,6-dimethoxybenzyl)-3-ethoxy-4-methyl-1,4-dihydropyrazino[2,1-b]quinazolin-6-one(870674-07-0)
• EPA Substance Registry System: (+)-(1R,4S)-1-(2-bromomethyl-3,6-dimethoxybenzyl)-3-ethoxy-4-methyl-1,4-dihydropyrazino[2,1-b]quinazolin-6-one(870674-07-0)

Safety Data

• Hazardous Substances Data: 870674-07-0(Hazardous Substances Data)

Upstream product

• 204770-99-0 (4S)-4-methyl-1,2,3,4-tetrahydro-5H-pyrazino[2,1-b]quinazoline-3,6-dione 
• 870673-94-2 (+)-(4S)-3-ethoxy-4-methyl-1,4-dihydropyrazino[2,1-b]quinazolin-6-one 
• 19164-83-1 1,4-dimethoxy-2,3-bis(bromomethyl)benzene 

Relevant articles and documents

A new stereocontrolled approach to fused polycyclic compounds containing a diketopiperazine ring

Representative (1S)- and (4S)-alkyl-1,4-dihydropyrazino[2,1-b]quinazoline- 3,6-dione lactim ethers were regio- and diastereoselectively alkylated after metallation to give the corresponding 1,4-trans-isomers with retention of the stereocentres. The result