870862-59-2

Upstream product

• 91738-34-0 2-C-(hydroxymethyl)-2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 870862-57-0 (1R,2R,3S,4S)-1-benzyloxy-4-(tert-butyldiphenylsilanyloxymethyl)-3,4-O-isopropylidenedioxy-2-methoxycyclohexane 
• 870862-47-8 (2S,3S,4R,5R)-2-C-(tert-butyldiphenylsilanyloxymethyl)-2,3:5,6-di-O-isopropylidene-D-mannofuranose 
• 870862-49-0 (2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene 
• 870862-48-9 (2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-6-hepten-3-ol 
• 870862-50-3 (2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-4,5-O-isopropylidenedioxy-6-heptene-1,2-diol 
• 870862-52-5 (3S,4R,5S,6S)-6-(tert-butyldiphenylsilanyloxymethyl)-5,6-O-isopropylidenedioxy-4-methoxy-1,7-octadien-3-ol 
• 870862-53-6 (3R,4R,5S,6S)-6-(tert-butyldiphenylsilanyloxymethyl)-5,6-O-isopropylidenedioxy-4-methoxy-1,7-octadien-3-ol 
• 870862-56-9 (1S,2R,3S,4S)-4-(tert-butyldiphenylsilanyloxymethyl)-3,4-O-isopropylidenedioxy-2-methoxycyclohexan-1-ol 
• 870862-51-4 (2S,3S,4S)-4-(tert-butyldiphenylsilanyloxymethyl)-3,4-O-isopropylidenedioxy-2-methoxy-5-hexenal 
• 870862-54-7 (1S,4S,5S,6R)-4-(tert-butyldiphenylsilanyloxymethyl)-4,5-O-isopropylidenedioxy-6-methoxy-2-cyclohexen-1-ol 
• 870862-55-8 (1R,4S,5S,6R)-4-(tert-butyldiphenylsilanyloxymethyl)-4,5-O-isopropylidenedioxy-6-methoxy-2-cyclohexen-1-ol 
• 870862-58-1 (1R,2R,3S,4S)-4-(tert-butyldiphenylsilanyloxymethyl)-3,4-O-isopropylidenedioxy-2-methoxycyclohexan-1-ol 

Downstream Products

• 870862-60-5 (1S,2S,3R,4R)-1-(triethylsilyloxymethyl)-2,4-di(triethylsilyloxy)-3-methoxy-1-cyclohexanol 
• 215370-56-2 (1S,2S,3R,4R)-1-hydroxymethyl-4-triethylsilyloxy-3-methoxy-1-cyclohexane-1,2-diol 
• 19683-98-8 (-)-ovalicin 

Relevant academic research and scientific papers

Synthesis of ovalicin starting from D-mannose

A new synthesis of epoxyketone 22 is described that is a key intermediate in Barton's synthesis of ovalicin (2), a powerful anti-angiogenetic inhibitor. The key process for the construction of 22 was ring-closing metathesis of olefins 11 and 12 obtained f