870991-47-2

Basic information

• Product Name: 4-phenyl-4-phenylsulfanyl-piperidine-1-carboxylic acid ethyl ester
• CAS NO: 870991-47-2
• Molecular Weight: 341.474
• Mol File: 870991-47-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-phenyl-4-phenylsulfanyl-piperidine-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-4-phenylsulfanyl-piperidine-1-carboxylic acid ethyl ester(870991-47-2)
• EPA Substance Registry System: 4-phenyl-4-phenylsulfanyl-piperidine-1-carboxylic acid ethyl ester(870991-47-2)

Safety Data

• Hazardous Substances Data: 870991-47-2(Hazardous Substances Data)

Upstream product

• 16332-22-2 ethyl 4-hydroxy-4-phenylpiperidine-1-carboxylate 
• 108-98-5 thiophenol 

Relevant articles and documents

Molecular-modeling based design, synthesis, and activity of substituted piperidines as γ-secretase inhibitors

Alzheimer's disease (AD) is a debilitating disease widely thought to be associated with the accumulation of beta amyloid (Aβ) in the brain. Inhibition of γ-secretase, one of the enzymes responsible for Aβ production, may be a useful strategy for the treatment of AD. Described below is a series of γ-secretase inhibitors designed from a scaffold identified by a ROCS [J. Comput. Chem. 1996, 17, 1653] search of the corporate database.