87116-20-9

Basic information

• Product Name: 1-<(Pivalyloxy)methoxy>-4-methoxybenzene
• Synonyms: 1-<(Pivalyloxy)methoxy>-4-methoxybenzene
• CAS NO: 87116-20-9
• Molecular Weight: 238.284
• Mol File: 87116-20-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-<(Pivalyloxy)methoxy>-4-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<(Pivalyloxy)methoxy>-4-methoxybenzene(87116-20-9)
• EPA Substance Registry System: 1-<(Pivalyloxy)methoxy>-4-methoxybenzene(87116-20-9)

Safety Data

• Hazardous Substances Data: 87116-20-9(Hazardous Substances Data)

Upstream product

• 18997-19-8 Chloromethyl pivalate 
• 53064-79-2 iodomethyl pivaloate 
• 150-76-5 4-methoxy-phenol 

Relevant articles and documents

Esterase-Activatable Synthetic M+/Cl? Channel Induces Apoptosis and Disrupts Autophagy in Cancer Cells

The formation of a supramolecular synthetic M+/Cl? channel in the membrane phospholipid bilayer has been reported upon activation of a methyl pivalate-linked N1,N3-dialkyl-2-hydroxyisophthalamide by esterases. The channel formation induces apoptosis in cancer cells via the intrinsic pathway. Interestingly, the supramolecular channel was also shown to disrupt autophagy in cancer cells by causing alkalization of lysosomes – a feature that has been confirmed at the cellular and protein level.