Cas 871235-48-2,4-[4-(2,4-dichloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic acid <i>tert</i>-butyl ester

871235-48-2

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Basic information

Product Name: 4-[4-(2,4-dichloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester
Synonyms: 4-[4-(2,4-dichloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester
CAS NO:871235-48-2
Molecular Formula:
Molecular Weight: 438.357
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-[4-(2,4-dichloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 4-[4-(2,4-dichloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester(871235-48-2)
EPA Substance Registry System: 4-[4-(2,4-dichloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester(871235-48-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 871235-48-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 871235-48-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,2,3 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 871235-48:
(8*8)+(7*7)+(6*1)+(5*2)+(4*3)+(3*5)+(2*4)+(1*8)=172
172 % 10 = 2
So 871235-48-2 is a valid CAS Registry Number.

871235-48-2Upstream product

57260-71-6 1-t-Butoxycarbonylpiperazine

871235-48-2Downstream Products

871235-45-9 (2,4-dichloro-benzyl)-(2-piperazin-1-yl-pyrimidin-4-yl)-amine

871235-48-2Relevant academic research and scientific papers

Optimization of CCR4 antagonists: Side-chain exploration

Purandare, Ashok V.,Wan, Honghe,Gao, Aiming,Somerville, John,Burke, Christine,Vaccaro, Wayne,Yang, Xiaoxia,McIntyre, Kim W.,Poss, Michael A.

, p. 204 - 207 (2007/10/03)

The design, synthesis, and activity of novel and selective small molecule antagonists of the CC chemokine receptor-4 (CCR4) are presented. Compound 8c was efficacious in a murine allergic inflammation model (ED50 30 mg/kg).

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