871237-03-5

Upstream product

• 951154-99-7 ((4S,5S,E)-5,7-bis(tert-butyldimethylsilyloxy)-4-methylhept-2-enyloxy)triphenylmethane 
• 591770-17-1 (2S,3S)-3,5-bis{[(tert-butyl)dimethylsilyl]oxy}-2-methylpentan-1-ol 
• 591770-18-2 (2S,3S)-3,5-bis{[(tert-butyl)dimethylsilyl]oxy}-2-methylpentyl 4-methylbenzenesulfonate 
• 188899-11-8 (3S)-3,5-bis{[(tert-butyl)dimethylsilyl]oxy}-2-methylpent-1-ene 
• 76-83-5 trityl chloride 
• 951154-98-6 (4S,5S,E)-5,7-bis(tert-butyldimethylsilyloxy)-4-methylhept-2-en-1-ol 
• 951154-97-5 ethyl (4S,5S,E)-5,7-bis(tert-butyldimethylsilyloxy)-4-methylhept-2-enoate 
• 911837-33-7 (2R,3S)-3,5-bis(tert-butyldimethylsilyloxy)-2-methylpentanal 

Downstream Products

• 871236-89-4 (2S,4S,5S)-4-[(2R,3S,6S,8R,9R,10S,11Z,13S,15S,16S,17E)-3,9,13,15-tetrakis(tert-butyldimethylsilyloxy)-6,8,10,16-tetramethyl-19-(trityloxy)nonadeca-11,17-dien-2-yl]-2-(4-methoxyphenyl)-5-methyl-1,3-dioxane 
• 871236-69-0 (3S,4S,E)-3-(tert-butyldimethylsilyloxy)-N-methoxy-N,4-dimethyl-7-(trityloxy)hept-5-enamide 
• 871236-70-3 (4S,5S,10S,11R,12R,14R,E)-11-(4-methoxybenzyloxy)-5,15-bis(tert-butyldimethylsilyloxy)-4,10,12,14-tetramethyl-1-(trityloxy)pentadec-2-en-8-yn-7-one 
• 871236-71-4 (4S,5S,7S,10S,11R,12R,14R,E)-11-(4-methoxybenzyloxy)-5,15-bis(tert-butyldimethylsilyloxy)-4,10,12,14-tetramethyl-1-(trityloxy)pentadec-2-en-8-yn-7-ol 
• 871236-72-5 (2E,4S,5S,7S,8Z,10S,11R,12R,14R)-11-(4-methoxybenzyloxy)-5,15-bis(tert-butyldimethylsilyloxy)-4,10,12,14-tetramethyl-1-(trityloxy)pentadeca-2,8-dien-7-ol 
• 871236-73-6 [(2E,4S,5S,7S,8Z,10S,11R,12R,14R)-11-(4-methoxybenzyloxy)-5,7,15-tris(tert-butyldimethylsilyloxy)-4,10,12,14-tetramethylpentadeca-2,8-dienyloxy]triphenylmethane 
• 871236-74-7 (2R,4R,5R,6S,7Z,11S,12S,13E)-1,9,11-tris(tert-butyldimethylsilyloxy)-2,4,6,12-tetramethyl-15-(trityloxy)pentadeca-7,13-dien-5-ol 
• 871236-75-8 [(2E,4S,5S,7S,8Z,10S,11R,12R,14R)-5,7,11,15-tetrakis(tert-butyldimethylsilyloxy)-4,10,12,14-tetramethylpentadeca-2,8-dienyloxy]triphenylmethane 
• 871236-76-9 (2R,4R,5R,6S,7Z,9S,11S,12S,13E)-5,9,11-tris(tert-butyldimethylsilyloxy)-2,4,6,12-tetramethyl-15-(trityloxy)pentadeca-7,13-dien-1-ol 
• 871236-77-0 (2R,4E,6R,8R,9R,10S,11Z,13S,15S,16S,17E)-9,13,15-tris(tert-butyldimethylsilyloxy)-2-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-6,8,10,16-tetramethyl-19-(trityloxy)nonadeca-4,11,17-trien-3-one 
• 871236-78-1 (2R,6S,8R,9R,10S,11Z,13S,15S,16S,17E)-9,13,15-tris(tert-butyldimethylsilyloxy)-2-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-6,8,10,16-tetramethyl-19-(trityloxy)nonadeca-11,17-dien-3-one 
• 871237-05-7 (2S,3R,6S,8R,9R,10S,11Z,13S,15S,16S,17E)-9,13,15-tris(tert-butyldimethylsilyloxy)-2-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-6,8,10,16-tetramethyl-19-(trityloxy)nonadeca-11,17-dien-3-ol 
• 871236-79-2 (2S,3S,6S,8R,9R,10S,11Z,13S,15S,16S,17E)-9,13,15-tris(tert-butyldimethylsilyloxy)-2-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-6,8,10,16-tetramethyl-19-(trityloxy)nonadeca-11,17-dien-3-ol 
• 871236-80-5 (2S,4S,5S)-4-[(2R,3R,6S,8R,9R,10S,11Z,13S,15S,16S,17E)-3,9,13,15-tetrakis(tert-butyldimethylsilyloxy)-6,8,10,16-tetramethyl-19-(trityloxy)nonadeca-11,17-dien-2-yl]-2-(4-methoxyphenyl)-5-methyl-1,3-dioxane 

Relevant academic research and scientific papers

Synthesis and biological evaluation of (-)-dictyostatin and stereoisomers

Total syntheses of (-)-dictyostatin, 6,16-bis-epi-dictyostatin, 6,14,19-tris-epi-dictyostatin, and a number of other isomers and analogs are reported. Three main fragments-top, middle, and bottom-were first assembled and then joined by olefination or anio