871252-65-2

Upstream product

• 871252-63-0 1-[4-(5-trifluoromethyl-pyridin-2-yl)-phenyl]-pentan-1-ol 
• 222610-47-1 N-(4-hydroxybenzoyl)-β-alanine methyl ester 

Downstream Products

• 871252-78-7 (S)-3-(4-{1-[4-(5-trifluoromethyl-pyridin-2-yl)-phenyl]-pentyloxy}-benzoylamino)-propionic acid methyl ester 
• 871252-76-5 (R)-3-(4-{1-[4-(5-trifluoromethyl-pyridin-2-yl)-phenyl]-pentyloxy}-benzoylamino)-propionic acid methyl ester 

Relevant academic research and scientific papers

GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES

The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.