871265-77-9Relevant academic research and scientific papers
Total synthesis of 12,13-desoxyepothilone B (Epothilone D)
Broadrup, Robert L.,Sundar, Hema M.,Swindell, Charles S.
, p. 116 - 133 (2005)
A highly convergent total synthesis of 12,13-desoxyepothilone B (4, Epothilone D) is described involving the coupling of vinyl iodide (5) and olefin (6). Key steps in the synthesis are the introduction of chirality at C15 via highly enantioselective lipas
