871268-89-2

Upstream product

• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 871268-84-7 (1R,2S,3S,4R,5R,7S)-3-Benzyloxy-7-benzyloxymethyl-2-hydroxy-5-propyl-4-triisopropylsilanyloxy-6-oxa-bicyclo[3.2.1]octan-8-one 
• 871268-82-5 (1R,2R,3S,4R,5R,7S)-3-Benzyloxy-7-benzyloxymethyl-2-hydroxy-5-propyl-4-triisopropylsilanyloxy-6-oxa-bicyclo[3.2.1]octan-8-one 
• 871268-78-9 (2S,3S,5S)-2-((1R,2S)-2-Benzyloxy-3-hydroxy-1-triisopropylsilanyloxy-propyl)-5-benzyloxymethyl-2-propyl-tetrahydro-furan-3-ol 
• 871268-80-3 (2R,3R)-2-Benzyloxy-3-((2R,5S)-5-benzyloxymethyl-3-oxo-2-propyl-tetrahydro-furan-2-yl)-3-triisopropylsilanyloxy-propionaldehyde 
• 871268-76-7 (1R,2S)-2-Benzyloxy-1-((2S,3S,5S)-5-benzyloxymethyl-3-hydroxy-2-propyl-tetrahydro-furan-2-yl)-propane-1,3-diol 
• 871268-88-1 (1R,3R,7S,8S,9R,10S,11R)-10-Benzyloxy-1-propyl-9-triethylsilanyloxy-11-triisopropylsilanyloxy-2-oxa-tricyclo[5.4.0.0^3,8]undecane-6,7-diol 
• 994-30-9 triethylsilyl chloride 
• 871268-98-3 (2S,3S,5S)-2-[(1R,2S)-2-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-triisopropylsilanyloxy-propyl]-5-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-propyl-tetrahydro-furan 
• 871268-99-4 (1S,2R,3S,4R,5R,7S)-3-Benzyloxy-7-benzyloxymethyl-5-propyl-2-triethylsilanyloxy-4-triisopropylsilanyloxy-6-oxa-bicyclo[3.2.1]octan-8-one 
• 871268-77-8 (1R,2S)-2-Benzyloxy-1-[(2R,3S,5S)-5-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-propyl-tetrahydro-furan-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-propan-1-ol 
• 871269-00-0 (E)-3-((1S,2R,3S,4R,5R,7R)-3-Benzyloxy-8-oxo-5-propyl-2-triethylsilanyloxy-4-triisopropylsilanyloxy-6-oxa-bicyclo[3.2.1]oct-7-yl)-propenal 
• 871268-86-9 3-((1S,2R,3S,4R,5R,7R)-3-Benzyloxy-8-oxo-5-propyl-2-triethylsilanyloxy-4-triisopropylsilanyloxy-6-oxa-bicyclo[3.2.1]oct-7-yl)-propionaldehyde 
• 871268-85-8 (1S,2R,3S,4R,5R,7S)-3-Benzyloxy-7-hydroxymethyl-5-propyl-2-triethylsilanyloxy-4-triisopropylsilanyloxy-6-oxa-bicyclo[3.2.1]octan-8-one 

Relevant academic research and scientific papers

Synthesis of the A-B subunit of angelmicin B

(Chemical Equation Presented) An efficient synthesis of the tricyclic A-B subunit 2 of angelmicin B is described. A formal three-component coupling of aldehydes 4 and 6 with γ-silylallylborane 7 was employed to assemble the tetrahydrofuranyl core of 2, a strategy highlighted by the stereoselective [3 + 2] annulation of allylsilanes 5a/5b with aldehyde 4. The efficiency of the [3 + 2] annulation was greatly improved by using the allylic benzhydryldimethylsilane 5b compared to the allylic phenyldimethylsilane 5a.