871302-55-5

Upstream product

• 85-43-8 1,2,3,6-Tetrahydrophthalic anhydride 
• 239807-63-7 α-(aminomethyl)-4-[2-(1-methylethoxy)phenyl]-1-piperazineethanol 
• 17620-38-1 2-oxiranylmethyl-3a,4,7,7a-tetrahydro-isoindole-1,3-dione 

Relevant academic research and scientific papers

METABOLITES OF 2-{3-[4-(2-ISOPROPOXYPHENYL) PIPERAZIN-1-YL]-PROPYL}-3A,4,7,7A-TETRAHYDRO-1H-ISOINDOLE-1,3-(2H)-DIONE

The present invention relates to the metabolites of 2-{3-[4-(2-isopropoxyphenyl) piperazin-1-yl]-propyl}-3a,4,7,7a -tetrahydro-1H-isoindole-1,3(2H)-dione of Formula I. The disclosed compounds can function as 1a-adrenoceptor antagonists and thus can be used for the treatment of benign prostatic hyperplasia (BPH) and related symptoms thereof. Processes for preparing the metabolites, pharmaceutical composition containing these metabolites and the method of treating BPH and related symptoms thereof are also provided.

ADRENERGIC RECEPTOR ANTAGONISTS

The present invention relates to α1a and/or α1d adrenergic receptor antagonists, which can function as α1a and/or α1d adrenergic receptor antagonist and can be used for the treatment of a disease or disorder med