871326-47-5 Usage
Chemical Class
The compound belongs to the thiazole class of organic compounds.
Structure
It is characterized by the presence of a thiazole ring and a carboxylic acid group.
Synthesis
The compound is derived from the reaction of 2,6-dichloroaniline with thiourea, followed by subsequent chlorination and carboxylation.
Uses
It is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.
Potential Applications
The compound has potential applications in the treatment of various diseases.
Antimicrobial Properties
It has been studied for its antimicrobial properties.
Anticancer Properties
It has been studied for its anticancer properties.
Further Research
Further research is needed to fully understand its potential uses and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 871326-47-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,3,2 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 871326-47:
(8*8)+(7*7)+(6*1)+(5*3)+(4*2)+(3*6)+(2*4)+(1*7)=175
175 % 10 = 5
So 871326-47-5 is a valid CAS Registry Number.
871326-47-5Relevant articles and documents
Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists
Xi, Ning,Bo, Yunxin,Doherty, Elizabeth M.,Fotsch, Christopher,Gavva, Narender R.,Han, Nianhe,Hungate, Randall W.,Klionsky, Lana,Liu, Qingyian,Tamir, Rami,Xu, Shimin,Treanor, James J.S.,Norman, Mark H.
, p. 5211 - 5217 (2007/10/03)
A thiazole derivative, 2-(2,6-dichlorobenzyl)-N-(4-isopropylphenyl) thiazole-4-carboxamide (1), was identified as a TRPV1 antagonist. We synthesized various thiazole analogs and evaluated them for their ability to block capsaicin- or acid-induced calcium influx in TRPV1-expressing CHO cells. The IC50 values of the most potent antagonists were ca. 0.050 μM in these assays.
