871332-18-2Relevant academic research and scientific papers
Synthesis of 2,4-diamino-1,3,5-triazine analogues of methotrexate with potential antitumor activity
Saczewski,Bulakowska
, p. 739 - 748 (2007/10/03)
A series of analogues of methotrexate 23-31 in which aminopteridine ring was replaced by 2,4-diamino-1,3,5-triazine moiety were obtained. The syntheses of the analogues were accomplished by alkylation of p-aminobenzoic acids with appropriate 6-bromomethyl
