871345-40-3Relevant academic research and scientific papers
Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors
Zbinden, Katrin Groebke,Obst-Sander, Ulrike,Hilpert, Kurt,Kuehne, Holger,Banner, David W.,Boehm, Hans-Joachim,Stahl, Martin,Ackermann, Jean,Alig, Leo,Weber, Lutz,Wessel, Hans Peter,Riederer, Markus A.,Tschopp, Thomas B.,Lave, Thierry
, p. 5344 - 5352 (2007/10/03)
We describe the structure-based design and synthesis of highly potent, orally bioavailable tissue factor/factor VIIa inhibitors which interfere with the coagulation cascade by selective inhibition of the extrinsic pathway.
N-(4- carbamimidoyl-phenyl) -glycine derivatives
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, (2008/06/13)
The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: wherein R1, E, X1 to X4 and G1 and G2 are as defined in the description and the claims, as well as hydrates or solvates and physiologically usable salts thereof.
