Basic information

Product Name: AS703569
Synonyms: AS703569;R763;Cenisertib;(1S,2S,3R,4R)-3-((5-fluoro-2-((3-Methyl-4-(4-Methylpiperazin-1-yl)phenyl)aMino)pyriMidin-4-yl)aMino)bicyclo[2.2.1]hept-5-ene-2-carboxaMide
CAS NO:871357-89-0
Molecular Formula: C24H30FN7O
Molecular Weight: 451.5397032
EINECS: N/A
Product Categories: N/A
Mol File: 871357-89-0.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 708.3±70.0 °C(Predicted)
Flash Point: N/A
Appearance: /
Density: 1.335±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
PKA: 16.24±0.40(Predicted)
CAS DataBase Reference: AS703569(CAS DataBase Reference)
NIST Chemistry Reference: AS703569(871357-89-0)
EPA Substance Registry System: AS703569(871357-89-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 871357-89-0(Hazardous Substances Data)

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Usage
SDS
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871357-89-0 Usage

Uses

Used in Pharmaceutical Industry:
AS703569 is used as an anti-cancer agent for its ability to inhibit the activity of aurora kinase, which is often overexpressed in cancer cells. This inhibition helps in controlling tumor growth and inducing apoptosis in cancer cells.
Used in Oncology Research:
AS703569 is used as a research tool for studying the role of aurora kinase in cell division and its involvement in cancer development. It aids in understanding the molecular mechanisms of cancer progression and identifying potential therapeutic targets.
Used in Combination Therapy:
AS703569 is used in combination with other anti-cancer treatments to enhance their efficacy. Its potential to induce apoptosis and inhibit tumor growth can complement the effects of conventional chemotherapy and radiotherapy, improving the overall treatment outcomes for cancer patients.

Check Digit Verification of cas no

The CAS Registry Mumber 871357-89-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,3,5 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 871357-89:
(8*8)+(7*7)+(6*1)+(5*3)+(4*5)+(3*7)+(2*8)+(1*9)=200
200 % 10 = 0
So 871357-89-0 is a valid CAS Registry Number.

871357-89-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	Cenisertib

1.2 Other means of identification

Product number	-
Other names	AS 703569

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:871357-89-0 SDS

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