871357-91-4

Usage

Uses

Used in Organic Chemistry:
(1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid is used as a building block for the synthesis of more complex organic molecules. Its unique structure and functional groups make it a valuable intermediate in the creation of novel compounds with specific properties and potential applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid is used as a precursor for the development of new drugs. Its specific stereochemistry and functional groups can be leveraged to design molecules with targeted therapeutic effects, potentially leading to the discovery of innovative treatments for various diseases.
Used in Materials Science:
(1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid is utilized in the field of materials science for the development of new materials with unique properties. Its incorporation into polymers or other materials can lead to the creation of advanced materials with applications in various industries, such as electronics, coatings, or biomedical devices.
Overall, (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid is a promising compound with a wide range of potential applications across different industries. Its unique structure and properties make it an interesting molecule for further study and exploration, with the potential to contribute to advancements in organic chemistry, pharmaceuticals, and materials science.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 202187-27-7 (1R,2R,3S,4S)-3-exo-aminobicyclo[2.2.1]hept-5-ene-2-exo-carboxylic acid 
• 790187-08-5 ethyl (1R,2R,3S,4S)-3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate 
• 14805-30-2 4-oxo-(1rC⁹,2tH,5tH,6cC⁹)-3-aza-tricyclo[4.2.1.0^2,5]non-7-ene-3-sulfonyl chloride 
• 121-46-0 bicyclo[2.2.1]hepta-2,5-diene 
• 14735-70-7 diexo-3-Aza-4-oxotricyclo<4.2.1.0^2,5>non-7-ene 
• 871357-90-3 (1SR,2SR,5RS,6RS)-4-oxo-3-aza-tricyclo[4.2.1.0(2,5)]non-7-ene-3-carboxylic acid tert-butyl ester 
• 1242184-48-0 Acide-3-exo-N-tert-butyloxycarbonylaminobicyclo<2.2.1>hept-5-ene-2-exo carboxylique 

Relevant academic research and scientific papers

Synthesis of novel N-heterocyclic compounds containing 1,2,3-triazole ring system via domino, “click” and RDA reactions

An uncomplicated, high-yielding synthetic route has been developed to constitute complicated heterocycles, applying domino, click and retro-Diels–Alder (RDA) reaction sequences. Starting from 2-aminocarboxamides, a new set of isoindolo[2,1-a]quinazolinones was synthesized with domino ring closure. A click reaction was performed to create the 1,2,3-triazole heterocyclic ring, followed by an RDA reaction resulting in dihydropyrimido[2,1-a]isoindole-2,6-diones. The absolute configuration, concluded by the norbornene structure that served as a chiral source, remained constant throughout the transformations. The structure of the synthesized compounds was examined by1H and13C Nuclear Magnetic Resonance (NMR) methods.

Mediators of hedgehog signaling pathways, compositions and uses related thereto

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.

Development and scale-up of an optimized route to the ALK inhibitor CEP-28122

Evolution of the process strategies to prepare CEP-28122, an anaplastic lymphoma kinase (ALK) inhibitor, is presented. The initial medicinal chemistry route, used for the preparation of key supplies for biological screening, is reviewed. In addition, the

Oligomers of cis-β-norbornene amino acid: Formation of β-strand mimetics

The oligomers of constrained cis-exo-β-norbornene amino acid were synthesised and characterised by extensive NMR, CD, IR and MD studies. The results showed the formation of both right and left handed consecutive 6-membered hydrogen-bonded strands for [2S,

Mediators of hedgehog signaling pathways, compositions and uses related thereto

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growt