871357-91-4

Basic information

• Product Name: (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
• Synonyms: (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
• CAS NO: 871357-91-4
• Molecular Formula: C₁₃H₁₉NO₄
• Molecular Weight: 253.29426
• Mol File: 871357-91-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid(871357-91-4)
• EPA Substance Registry System: (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid(871357-91-4)

Safety Data

• Hazardous Substances Data: 871357-91-4(Hazardous Substances Data)

Usage

General Description

The chemical "(1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid" is a compound with a complex and specific structure. It contains a bicyclic ring system and a carboxylic acid group, as well as a tert-butoxycarbonylamino functional group. (1R,2R,3S,4S)-3-(tert-Butoxycarbonylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid is likely to have unique properties and potential applications in the fields of organic chemistry, pharmaceuticals, and materials science. Its synthesis and characterization would require specialized techniques and expertise due to its intricate structure and functional groups. Overall, this compound represents an interesting and potentially valuable molecule for further study and exploration.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 202187-27-7 (1R,2R,3S,4S)-3-exo-aminobicyclo[2.2.1]hept-5-ene-2-exo-carboxylic acid 
• 871357-90-3 (1SR,2SR,5RS,6RS)-4-oxo-3-aza-tricyclo[4.2.1.0(2,5)]non-7-ene-3-carboxylic acid tert-butyl ester 
• 14735-70-7 diexo-3-Aza-4-oxotricyclo<4.2.1.0^2,5>non-7-ene 
• 121-46-0 bicyclo[2.2.1]hepta-2,5-diene 
• 14805-30-2 4-oxo-(1rC⁹,2tH,5tH,6cC⁹)-3-aza-tricyclo[4.2.1.0^2,5]non-7-ene-3-sulfonyl chloride 
• 1242184-48-0 Acide-3-exo-N-tert-butyloxycarbonylaminobicyclo<2.2.1>hept-5-ene-2-exo carboxylique 
• 790187-08-5 ethyl (1R,2R,3S,4S)-3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate 

Relevant articles and documents

Synthesis of novel N-heterocyclic compounds containing 1,2,3-triazole ring system via domino, “click” and RDA reactions

An uncomplicated, high-yielding synthetic route has been developed to constitute complicated heterocycles, applying domino, click and retro-Diels–Alder (RDA) reaction sequences. Starting from 2-aminocarboxamides, a new set of isoindolo[2,1-a]quinazolinones was synthesized with domino ring closure. A click reaction was performed to create the 1,2,3-triazole heterocyclic ring, followed by an RDA reaction resulting in dihydropyrimido[2,1-a]isoindole-2,6-diones. The absolute configuration, concluded by the norbornene structure that served as a chiral source, remained constant throughout the transformations. The structure of the synthesized compounds was examined by1H and13C Nuclear Magnetic Resonance (NMR) methods.

Development and scale-up of an optimized route to the ALK inhibitor CEP-28122

Evolution of the process strategies to prepare CEP-28122, an anaplastic lymphoma kinase (ALK) inhibitor, is presented. The initial medicinal chemistry route, used for the preparation of key supplies for biological screening, is reviewed. In addition, the

Mediators of hedgehog signaling pathways, compositions and uses related thereto

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growt