87145-45-7Relevant academic research and scientific papers
Ligand dissociation as a preliminary step in methyl for halogen exchange reactions of platinum(II) complexes
Scott, John D.,Puddephatt, Richard J.
, p. 1643 - 1648 (2008/10/08)
The complex cis-[PtMe2(SMe2)2] exists in solution in equilibrium with [Pt2Me4(μ-SMe2)2] and free SMe2. Methyl for halogen exchange occurs on reaction of cis-[PtMe2(SMe2)2] with cis- or trans-[PtCl2(SMe2)2] to give trans-[PtClMe(SMe2)2] as the only product, with trans-[PtI2(SMe2)2] to give trans-[PtIMe(SMe2)2], and with trans-[PtI2(PMePh2)2] to give isomers of [PtIMe(SMe2)(PMePh2)] as major projects, whereas cis-[PtMe2(PMe2Ph)2] reacts with trans-[PtI2(SMe2)2] to give trans-[PtIMe(PMe2Ph)2] and trans-[PtIMe(SMe2)2] with no scrambling of neutral ligands. Kinetic studies show that the reaction of cis-[PtMe2(SMe2)2] with trans-[PtCl2(SMe2)2] follows second-order kinetics (first order in each reagent) and the reaction is strongly retarded in the presence of free SMe2. From these results, it is deduced that the methyl for halogen exchange reactions of cis-[PtMe2(SMe2)2] occur after dissociation of SMe2 to give a reactive intermediate, [PtMe2(SMe2)].
