871476-83-4Relevant academic research and scientific papers
COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING URIC ACID LEVELS
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Page/Page column 72-73, (2010/12/18)
Described herein are compounds useful in the reduction of blood uric acid levels, formulations containing them and methods of making and using them. In some embodiments, the compounds described herein are used in the treatment or prevention of disorders related to aberrant levels of uric acid.
Investigation on the role of the tetrazole in the binding of thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases
Gagnon, Alexandre,Landry, Serge,Coulombe, Rene,Jakalian, Araz,Guse, Ingrid,Thavonekham, Bounkham,Bonneau, Pierre R.,Yoakim, Christiane,Simoneau, Bruno
scheme or table, p. 1199 - 1205 (2009/08/07)
The role of the tetrazole moiety in the binding of aryl thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases was explored. Different acyclic, cyclic and heterocyclic replacements were investigated in order t
NON NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
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Page/Page column 97, (2008/06/13)
The invention relates to compounds of formula (I) wherein Ar, X, R1, R2, R3 and R4 are as defined herein and, pharmaceutical compositions thereof useful, either alone or in combination with other therapeutic agents as reverse transcriptase inhibitors against wild type and single or double mutant strains of HIV for the treatment or prophylaxis of HIV infection
