871483-75-9Relevant academic research and scientific papers
Design, synthesis, and evaluation of octahydropyranopyrrole-based inhibitors of mammalian ribonucleotide reductase
Fuertes, Michael J.,Kaur, Jaskiran,Deb, Prasant,Cooperman, Barry S.,Smith III, Amos B.
, p. 5146 - 5149 (2007/10/03)
Inhibitors of mammalian ribonucleotide reductase possessing a novel octahydropyranopyrrole scaffold based on a cyclic heptapeptide inhibitor have been designed, synthesized, and evaluated. Structure-function studies reveal that the bicyclic scaffold is in
