871553-26-3

Upstream product

• 871553-24-1 ethyl 4-amino-5-(4-aminophenyl)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate 
• 1885-14-9 phenyl chloroformate 
• 871553-14-9 ethyl 4-(4-nitrophenyl)-1H-pyrrole-3-carboxylate 
• 871553-17-2 ethyl 5-formyl-4-(4-nitrophenyl)-1H-pyrrole-3-carboxylate 
• 871553-19-4 ethyl 5-cyano-4-(4-nitrophenyl)-1H-pyrrole-3-carboxylate 
• 871553-22-9 ethyl 1-amino-5-cyano-4-(4-nitrophenyl)-1H-pyrrole-3-carboxylate 
• 871553-12-7 ethyl 4-amino-5-(4-nitrophenyl)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate 
• 24393-61-1 ethyl (E)-3-(4-nitrophenyl)-2-propenoate 

Downstream Products

• 871553-30-9 ethyl 4-amino-5-{4-[({[2-fluoro-5-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenyl}pyrrolo[2,1-f]-[1,2,4]triazine-6-carboxylate 
• 871553-32-1 N-[4-(4-amino-6-formylpyrrolo[2,1-f][1,2,4]triazin-5-yl)phenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea 
• 871553-34-3 N-{4-[4-amino-6-(hydroxymethyl)pyrrolo[2,1-f][1,2,4]triazin-5-yl]phenyl}-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea 
• 871553-36-5 4-amino-5-{4-[({[2-fluoro-5-(trifluoromethyl)-phenyl]amino}carbonyl)amino]phenyl}pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid 

Relevant academic research and scientific papers

PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS

This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.