871555-38-3

Upstream product

• 871553-24-1 ethyl 4-amino-5-(4-aminophenyl)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate 
• 857265-11-3 phenyl N-[4-(trifluoromethyl)pyridin-2-yl]carbamate 

Downstream Products

• 871557-16-3 N-[4-(4-amino-6-vinylpyrrolo[2,1-f][1,2,4]triazin-5-yl)phenyl]-N'-[4-(trifluoromethyl)pyridin-2-yl]urea 
• 871554-36-8 N-[4-(4-amino-6-formylpyrrolo[2,1-f][1,2,4]-triazin-5-yl)phenyl]-N'-[4-(trifluoromethyl)pyridin-2-yl]urea 
• 871554-34-6 N-{4-[4-amino-6-(hydroxymethyl)pyrrolo[2,1-f][1,2,4]triazin-5-yl]phenyl}-N'-[4-(trifluoromethyl)pyridin-2-yl]urea 

Relevant academic research and scientific papers

SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS

This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.