87160-28-9Relevant academic research and scientific papers
Reactions of Complex Ligands, XXIII. Bis(phosphino)indene Derivatives from Carbon Carbon Bond Formation between Arylcarbene Ligands and Bis(diphenylphosphino)acetylene
Doetz, Karl Heinz,Pruskil, Ingrid,Schubert, Ulrich,Ackermann, Klaus
, p. 2337 - 2343 (2007/10/02)
Pentacarbonyl(methoxyphenylcarbene) complexes of chromium and tungsten (1a, 2a) react with bis(diphenylphosphino)acetylene (3) via CO substitution to give binuclear alkyne bridged bis(carbene) complexes (CO)4M-C-P(C6H5)2>-M(CO)4 (4a, 5a).The chromium compound 4a is cleaved on warming to yield the tetracarbonylchromium complex 6a and 1a. In a one-pot reaction the bis(phosphino)indene derivatives 6a-c are formed directly from arylcarbene chromium complexes(CO)5Cr (R = H, CH3, CF3) (1a-c) and 3.The structure of 6c is established by X-ray analysis.
CARBON-CARBON BOND FORMATION VIA CARBONYL-CARBENE COMPLEXES.
Doetz
, p. 1689 - 1706 (2008/10/08)
The synthetic potential of carbonyl carbene complexes is demonstrated upon their reaction with alkynes. Both the elecrophilicity of the carbene carbon atom and the facile substitution of carbon monoxide are used for selective carbon-carbon bond formation. Nucleophilic alkynes (ynamines) add to the carbene carbon atom and then undergo insertion into the metal carbene bond. Chromium(0) is effective as a template in the annulation of carbene ligands bearing aromtic or vinylic side chains: Metal-assisted carbene transfer or both carbene and carbonyl transfer to alkynes are observed to yield indenes or 1,4-hydroquinones. The hydroquinone formation occurs regioselectively with respect to the alkyne incorporation and the annulation of diarylcarbene ligands. The synthetic utility of this reaction is exemplified by the synthesis of vitamins K and E.
