871671-10-2Relevant academic research and scientific papers
Synthesis of (R)-(-)-2-fluoronorapomorphine - A precursor for the synthesis of (R)-(-)-2-fluoro-N-[11C]propylnorapomorphine for evaluation as a dopamine D2 agonist ligand for PET investigations
Sondergaard, Kare,Kristensen, Jesper Langgaard,Gillings, Nic,Begtrup, Mikael
, p. 4428 - 4433 (2007/10/03)
2-Fluoronorapomorphine, the PET labelling precursor to 2-fluoro-N-[ 11C]propylnorapomorphine, was prepared in 13 steps from codeine in a total yield of 10 %. Codeine was converted in four steps into N-benzylnorcodeine which was oxidised by usin
