871682-96-1Relevant academic research and scientific papers
Construction of quaternary stereocenters by efficient and practical conjugate additions to α,β-unsaturated ketones with a chiral organic catalyst
Wu, Fanghui,Li, Hongming,Hong, Ran,Deng, Li
, p. 947 - 950 (2006)
(Chemical Equation Presented) Added value: The conjugate addition of cyclic or acyclic α-substituted β-ketoesters to α,β-unsaturated ketones using a chiral organic catalyst (1) can be achieved with good enantioselectivity, diastereoselectivity, and yield. This asymmetric C-C bond formation strategy provides a range of chiral building blocks 2 that contain an all-carbon quaternary stereocenter.
