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1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea is a chemical compound characterized by the molecular formula C10H10FN2OI. It is a urea derivative featuring a cyclopropyl group attached to a phenyl ring that is substituted with both fluorine and iodine atoms. This unique molecular structure endows it with potential applications in pharmaceutical research and development, particularly in the realms of anti-cancer and anti-inflammatory medications. Its functional groups and structural attributes make it a significant compound for exploring structure-activity relationships of drug candidates and for investigating its own possible biological activities for therapeutic uses.

871700-18-4

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871700-18-4 Usage

Uses

Used in Pharmaceutical Research and Drug Development:
1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea serves as a valuable research tool in the pharmaceutical industry for its potential role in the development of anti-cancer and anti-inflammatory medications. Its distinct molecular structure allows for the investigation of how slight modifications can influence a compound's pharmacological properties, thereby aiding in the discovery of more effective and safer drugs.
Used in Structure-Activity Relationship Studies:
In the field of medicinal chemistry, 1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea is utilized as a model compound to study the relationship between a drug's chemical structure and its biological activity. Understanding these relationships is crucial for optimizing drug efficacy and minimizing side effects.
Used in Anti-cancer Medications:
1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea is considered for use as an anti-cancer agent, given its potential to interact with biological targets implicated in cancer progression. The presence of the cyclopropyl group and the halogenated phenyl ring may contribute to its ability to modulate cellular processes related to tumor growth and survival.
Used in Anti-inflammatory Applications:
Given its structural features, 1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea may also be explored for its anti-inflammatory properties. The cyclopropyl urea scaffold could offer a novel approach to managing inflammation by targeting specific inflammatory pathways or enzymes.

Check Digit Verification of cas no

The CAS Registry Mumber 871700-18-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,7,0 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 871700-18:
(8*8)+(7*7)+(6*1)+(5*7)+(4*0)+(3*0)+(2*1)+(1*8)=164
164 % 10 = 4
So 871700-18-4 is a valid CAS Registry Number.

871700-18-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea

1.2 Other means of identification

Product number -
Other names Urea,N-cyclopropyl-N'-(2-fluoro-4-iodophenyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:871700-18-4 SDS

871700-18-4Relevant academic research and scientific papers

5-AMINO-2,4,7-TRIOXO-3,4,7,8-TETRAHYDRO-2H-PYRIDO’2,3-D! PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF CANCER

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Page/Page column 144; 149-150, (2008/06/13)

The present invention relates to a pyrimidine compound represented by the following formula [I] wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof, and a pharmaceutical agent for the prophylaxis or treatment of a disease caused by undesirable cell proliferation, particularly an antitumor agent, which contains such compound. The compound of the present invention has superior undesirable cell proliferation suppressing action, particularly, an antitumor action, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, antirheumatoid agent and the like. In addition, by the combined use with other antitumor agent such as alkylating agent, metabolism antagonist and the like, it can be a more effective antitumor agent.

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