871708-18-8

Basic information

• Product Name: 5-(3-Amino-1H-indazol-5-yl)furan-2-carboxylic acid
• Synonyms: 5-(3-Amino-1H-indazol-5-yl)furan-2-carboxylic acid;5-(3-amino-1H-indazol-5-yl)-2-Furancarboxylic acid
• CAS NO: 871708-18-8
• Molecular Formula: C₁₂H₉N₃O₃
• Molecular Weight: 243.21816
• Mol File: 871708-18-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(3-Amino-1H-indazol-5-yl)furan-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-Amino-1H-indazol-5-yl)furan-2-carboxylic acid(871708-18-8)
• EPA Substance Registry System: 5-(3-Amino-1H-indazol-5-yl)furan-2-carboxylic acid(871708-18-8)

Safety Data

• Hazardous Substances Data: 871708-18-8(Hazardous Substances Data)

Upstream product

• 871709-97-6 5-(3-cyano-4-fluorophenyl)-furane-2-carboxylic acid 
• 7803-57-8 hydrazine hydrate 
• 105942-08-3 4-bromo-6-fluorobenzonitrile 
• 214210-21-6 3-cyano-4-fluorophenylboronic acid 
• 585-70-6 5-bromo-furan-2-carboxylic acid 

Downstream Products

• 884874-70-8 5-(3-amino-1H-indazol-5-yl)-furan-2-carboxylic acid N-(3-hydroxy-benzyl)amide 

Relevant articles and documents

INDAZOLE-HETEROARYL DERIVATIVES

The invention relates to novel indazole derivatives as cited in claim 1, which are inhibitors of CHK1, CHK2 and SGK kinases and can be used to treat cancer and other diseases.

HETEROCYCLIC CARBONYL COMPOUNDS

The invention relates to novel heterocyclic compounds of formula (I) wherein R1, D, W, T and T' have the meaning cited in the claim 1. Said compounds are SGK-inhibitors and can be used in the treatment of SGK-related diseases and disorders such as diabetes, obesity, metabolic syndrome (dyslipidemia), systemic and pulmonal hypertension, cardiovascular diseases and renal diseases, and generally for any kind of fibroses and inflammatory processes.