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γ,γ-Di-tert-butyl-L-γ-carboxyglutamic Acid α-Methyl Ester p-Toluenesulfonate Salt is a complex organic compound with the molecular formula C18H31NO6S. It is a derivative of glutamic acid, an essential amino acid, featuring a γ-carboxy group and a γ,γ-di-tert-butyl group, which provides increased steric hindrance and stability. The α-methyl ester group enhances the lipophilicity, while the p-toluenesulfonate salt form improves solubility in organic solvents. γ,γ-Di-tert-butyl-L-γ-carboxyglutamic Acid α-Methyl Ester p-Toluenesulfonate Salt is often used in the synthesis of pharmaceuticals, particularly in the development of inhibitors targeting various enzymes, such as matrix metalloproteinases (MMPs), due to its ability to mimic the structure of the glutamic acid residue in peptide substrates. Its unique structure allows for the design of selective and potent inhibitors, making it a valuable tool in medicinal chemistry and drug discovery.

87173-10-2

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87173-10-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 87173-10-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,1,7 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 87173-10:
(7*8)+(6*7)+(5*1)+(4*7)+(3*3)+(2*1)+(1*0)=142
142 % 10 = 2
So 87173-10-2 is a valid CAS Registry Number.

87173-10-2Relevant academic research and scientific papers

Synthetic Studies on Sequences of Vitamin K Dependent Proteins. Gla-Arg-Gla Sequences

Craig, Daniel H.,Koehler, Karl A.,Hiskey, Richard G.

, p. 3954 - 3957 (2007/10/02)

The synthesis of peptides containing the Gla-Arg-Gla sequence is reported.Nuclear magnetic resonance studies suggest that intramolecular salt bridge interactions occur between the guanidino group of arginine and the γ-carboxyglutamic acid.

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