871794-84-2

Upstream product

• 10378-08-2 ethyl 6-(benzyloxy)-3-oxohexanoate 
• 10385-30-5 4-(benzyloxy)butanoic acid 
• 771431-34-6 C₁₃H₁₆O₄ 
• 871794-83-1 6-(3-benzyloxy-propyl)-2-mercapto-pyrimidin-4-ol 
• 74-88-4 methyl iodide 

Downstream Products

• 871794-85-3 trifluoro-acetic acid 6-(3-benzyloxy-propyl)-2-methylsulfanyl-pyrimidin-4-yl ester 
• 871794-88-6 4-(3-benzyloxy-propyl)-6-trimethylstannanyl-pyrimidine-2-carbonitrile 
• 871794-87-5 4-(3-benzyloxy-propyl)-2-methanesulfonyl-6-trimethylstannanyl-pyrimidine 
• 871794-86-4 trifluoro-acetic acid 6-(3-benzyloxy-propyl)-2-methanesulfonyl-pyrimidin-4-yl ester 

Relevant academic research and scientific papers

4-PHENYL-PYRIMIDINE-2-CARBONITRILE DERIVATIVES

The invention relates to 4-phenyl-pyrimidine-2-carbonitrile derivatives having the general formula (I) or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives as well as to the use thereof in the preparation of a medicament suitable for the treatment of osteoporosis, atherosclerosis, inflammation and immune disorders, such as rheumatoid arthritis, and chronic pain, such as neuropathic pain.