871819-35-1 Usage
Uses
Used in Pharmaceutical Research:
4,7-DIBROMO-5-AZAINDOLE is utilized as a key intermediate in the synthesis of various pharmaceutical compounds, particularly for the development of anti-cancer and anti-inflammatory drugs. Its unique chemical properties allow for the creation of novel therapeutic agents that can target specific biological pathways and mechanisms.
Used in Organic Synthesis:
In the field of organic synthesis, 4,7-DIBROMO-5-AZAINDOLE is employed as a versatile building block for the construction of complex organic molecules. Its reactivity and structural features enable the synthesis of a wide range of compounds with diverse applications in various industries.
Used in Dye and Pigment Production:
4,7-DIBROMO-5-AZAINDOLE is used as a starting material in the preparation of dyes and pigments, owing to its ability to impart color and stability to various products. Its presence in these compounds contributes to their performance and longevity in different applications.
Used in Agricultural Chemicals:
In the agricultural sector, 4,7-DIBROMO-5-AZAINDOLE is employed in the development of agricultural chemicals, such as pesticides and herbicides. Its unique properties allow for the creation of effective and targeted solutions to address various agricultural challenges.
Overall, 4,7-DIBROMO-5-AZAINDOLE's diverse applications across pharmaceutical, organic synthesis, dye and pigment production, and agricultural chemical industries highlight its significance and potential in advancing scientific and technological developments.
Check Digit Verification of cas no
The CAS Registry Mumber 871819-35-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,8,1 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 871819-35:
(8*8)+(7*7)+(6*1)+(5*8)+(4*1)+(3*9)+(2*3)+(1*5)=201
201 % 10 = 1
So 871819-35-1 is a valid CAS Registry Number.
871819-35-1Relevant academic research and scientific papers
Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin- 7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain
Giblin, Gerard M. P.,Billinton, Andrew,Briggs, Michael,Brown, Andrew J.,Chessell, Iain P.,Clayton, Nick M.,Eatherton, Andrew J.,Goldsmith, Paul,Haslam, Carl,Johnson, Matthew R.,Mitchell, William L.,Naylor, Alan,Perboni, Alcide,Slingsby, Brian P.,Wilson, Alex W.
supporting information; experimental part, p. 5785 - 5788 (2010/02/28)
We report the synthesis and SAR of a series of novel azaindole CB 2 agonists. 6-Azaindole 18 showed activity in an acute pain model but was inactive in a chronic model. 18 is a Pgp substrate with low brain penetration. The template was redesign
PYRROLOPYRIDINE DERIVATIVES
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Page/Page column 50, (2008/06/13)
The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.