871829-76-4

Upstream product

• 153624-46-5 4-(isopropoxy)phenylboronic acid 
• 16732-70-0 ethyl 5-bromoindolecarboxylate 
• 871829-77-5 1,5-bis(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester 
• 825624-93-9 3-bromo-5-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided a compound of formula: (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.

INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided a compound of formula: (I) wherein X, Rl, R2, R3, R4, R5, R6, R7 and R8 have meanings given in the description, and pharmaceutically-acceptable salts