871829-80-0

Upstream product

• 91062-61-2 5-bromo-3-chloro-indole-2-carboxylic acid ethyl ester 
• 153624-46-5 4-(isopropoxy)phenylboronic acid 

Downstream Products

• 871829-82-2 3-chloro-1-(4-isopropoxyphenyl)-5-(5-trifluoromethylpyrid-2-yl)-1H-indole-2-carboxylic acid ethyl ester 
• 871829-81-1 3-chloro-5-(dihydroxyboryl)-1-(4-isopropoxyphenyl)-1H-indole-2-carboxylic acid ethyl ester 
• 902757-48-6 3-chloro-1-(4-isopropoxyphenyl)-5-(2-phenylcyclopropyl)indole-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I): wherein X1, R1, R2, R3, R4, R5, T and Y have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds ar

INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), Wherein X1 , R1 , R2 , R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein X1, T, Y, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds ar

INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided a compound of formula: (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.