87184-63-2Relevant academic research and scientific papers
Ethyl glyoxylate N -tosylhydrazone as sulfonyl-transfer reagent in base-catalyzed sulfa-Michael reactions
Fernandez, Maitane,Uria, Uxue,Orbe, Lucia,Vicario, Jose L.,Reyes, Efraim,Carrillo, Luisa
, p. 441 - 445 (2014/01/17)
Ethyl glyoxylate N-tosylhydrazone has been identified as an excellent sulfonyl anion surrogate in the DBU-catalyzed conjugate addition reaction with enones and enals for the synthesis of functionalized sulfones. The reaction proceeds under base-catalyzed conditions and provides a direct access to γ-keto- and γ-hydroxy sulfones in a simple and reliable way through a sulfa-Michael reaction that proceeds with high yield and chemoselectivity.
A study of the intramolecular cyclization reactions of some derivatives of 3-arylsulfonyl cycloalkanols
Gonzales, Stephen S.,Jacobs, Hollie K.,Juarros, LuAnne E.,Gopalan, Aravamudan S.
, p. 6827 - 6830 (2007/10/03)
Carbonate and acyl derivatives of 3-arylsulfonylcyclohexanols and heptanols, upon deprotonation with LHMDS in THF at -78°C, undergo an intramolecular cyclization reaction to give bicyclic lactones or the corresponding acyl transfer products in synthetically useful yields. In contrast, the corresponding cyclopentyl derivatives show different reactivity.
Preparation and Stereochemistry of Methylation of Some Cycloalkyl Sulfones
Rothberg, Irvin,Sundoro, Boby,Balanikas, George,Kirsch, Sheldon
, p. 4345 - 4348 (2007/10/02)
3-((4-methylphenyl)sulfonyl)cyclohexanols (2, 3), 3-((4-methylphenyl)sulfonyl)cyclopentanols (7, 8), and 2-((4-methylphenyl)sulfonyl)cyclopentanols (12, 15) and their tetrahydropyranyl ether derivatives were prepared.Attempted methylation of the tetrahydr
