871940-17-9

Upstream product

• 156-59-2 cis-1,2-Dichloroethylene 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 1272413-31-6 (Z)-7-(4-methoxyphenyl)-1-phenylhepta-4-en-2,6-diyn-1-one 
• 1272413-40-7 (Z)-1,7-bis(4-methoxyphenyl)hepta-4-en-2,6-diyn-1-one 
• 1272413-54-3 7-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyridine 
• 1272413-58-7 2,7-bis(4-methoxyphenyl)pyrazolo[1,5-a]pyridine 
• 1272413-35-0 (Z)-1,7-bis(4-methoxyphenyl)hepta-4-en-2,6-diyn-1-ol 
• 1272413-18-9 (Z)-7-(4-methoxyphenyl)-1-phenylhepta-4-en-2,6-diyn-1-ol 
• 1450991-03-3 (Z)-1-methoxy-4-(5-phenylpent-3-en-1-yn-1-yl)benzene 

Relevant academic research and scientific papers

Synthesis of 1,5-diphenylpent-3-en-1-yne derivatives utilizing an aqueous B-alkyl Suzuki cross coupling reaction

1,5-Diphenylpent-3-en-1-yne derivatives were isolated in minor quantities from terrestrial plants and exhibited strong anti-inflammatory activity. A cross coupling reaction between B-benzyl-9-BBN and chloroenynes under mild condition was developed resulti

A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines

2,7-Disubstituted pyrazolo[1,5-a]pyridines were synthesized in good chemical yields by the reaction of enediynones with hydrazine, followed by addition of copper chloride. This reaction can tolerate many functional groups.

Synthetic approach to enyne and enediyne analogues of anticancer agents

The synthesis and the anticancer activity of a new kind of enynes 2 and 3 and enediynes 4, analogues of Combretastatin A-4 1 are reported and discussed.