871946-59-7Relevant academic research and scientific papers
Design, synthesis, and microbiological evaluation of new Candida albicans CYP51 inhibitors
Schiaffella, Fausto,Macchiarulo, Antonio,Milanese, Lara,Vecchiarelli, Anna,Costantino, Gabriele,Pietrella, Donatella,Fringuelli, Renata
, p. 7658 - 7666 (2005)
In a program aimed at the design and synthesis of novel azole inhibitors of Candida albicans CYP51 (CA-CYP51), a series of azole 1,4-benzothiazines (BT) and 1,4-benzoxazines (BO) were recently synthesized. A morphological study of the enzyme active site h
